As the fetal heart during development of disturbance so that part of the development of a standstill or defects, and some were unable to complete degradation of the degradation caused by .

        Environmental factors surrounding a fetus within the uterus during early pregnancy to rubella virus infection after infection, often caused by more common patent ductus arteriosus and pulmonary stenosis followed by the Coxsackie virus (Coxsakie) can cause endocardial fibroelastosis In addition, amniotic membrane mechanical pressure around the lesion of fetal maternal nutrition, vitamin deficiency and metabolic diseases barriers to maternal use cytotoxic drugs, or a longer time may be related to radiation exposure are related Benbingfasheng .

2 5% of genetic factors in patients with congenital heart disease occurred in the same family the same or similar kinds of their disease may be due to genetic anomalies or chromosomal aberrations caused by

   Three other highland areas of patent ductus arteriosus and atrial septal defect that may have a higher prevalence of congenital heart disease and hypoxia related to some gender-biased